Delassalle A, Cesselin F, Carayon A, Legrand S, Antreassian J, Lagoguey A, Legrand J C, Desgrez P
C R Seances Soc Biol Fil. 1976;170(4):745-50.
A radioimmunoassay for urinary tetrahydroaldosterone is described. An antiserum, elicited by a 3-carboxy-methyloxime 18-21 aldosterone diacetate conjugated to bovine serumalbumine, with which tetrahydroaldosterone cross reacts, is used. The method is specific, sensitive (10 pg/tube), accurate, reproducible (7%), thus allowing sufficient reliability for clinical applications. In 19 normal adults subjects under unrestricted sodium intake, the urinary tetrahydroaldosterone averaged 59,8+/-29,4 mug/24 h.
本文描述了一种尿四氢醛固酮的放射免疫测定法。使用的抗血清是由与牛血清白蛋白偶联的3-羧甲基肟18-21醛固酮二乙酸酯引发的，四氢醛固酮与之发生交叉反应。该方法具有特异性、灵敏性（10皮克/管）、准确性、可重复性（7%），因此在临床应用中具有足够的可靠性。在19名钠摄入不受限制的正常成年人中，尿四氢醛固酮平均为59.8±29.4微克/24小时。
