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[肿瘤所致气道阻塞的姑息治疗措施]

[Palliative measures in tumor-induced obstruction of the airways].

作者信息

Bolliger C T, Probst R, Perruchoud A P

机构信息

Abteilung für Pneumologie, Departement Innere Medizin, Universitätskliniken Basel.

出版信息

Schweiz Rundsch Med Prax. 1992 Jan 7;81(1-2):15-9.

PMID:1370588
Abstract

Local stenoses of the central airways in malignant inoperable disease are sometimes present at the time of diagnosis or develop over time after the completion of systemic palliative treatment. These stenoses should be relieved by local means in order to prevent the development of atelectasis and poststenotic pneumonia. Otherwise, patients will develop progressive dyspnea, and their general condition will decline rapidly. Various methods aimed at the relief of local obstructions exist and are often used in combination. Most procedures are performed under general anaesthesia using the rigid bronchoscope. Intraluminal obstructions can be relieved by laser-, cryo- and brachytherapy (endobronchial radiation). Extrinsic stenoses caused by airway compression from outside or by thickening of the airway wall through submucosal tumor growth must be dilated. At the end of these procedures, the insertion of silicone stents is ideally suited to maintain airway patency in dilated extrinsic stenoses and to prevent recurrent intraluminal tumor growth after laser therapy. The various methods aimed at the relief of malignant local airway obstructions are discussed, with emphasis on the recently developed silicone stents.

摘要

恶性不可手术疾病的中央气道局部狭窄有时在诊断时就已存在,或在全身姑息治疗完成后随时间发展而来。这些狭窄应通过局部手段予以解除,以防止肺不张和狭窄后肺炎的发生。否则,患者会出现进行性呼吸困难,其一般状况将迅速恶化。存在多种旨在解除局部梗阻的方法,且常联合使用。大多数操作在全身麻醉下使用硬支气管镜进行。腔内梗阻可通过激光、冷冻和近距离放射治疗(支气管内放射)来解除。由外部气道压迫或黏膜下肿瘤生长导致气道壁增厚引起的外部狭窄必须进行扩张。在这些操作结束时,插入硅酮支架非常适合维持扩张后的外部狭窄气道的通畅,并防止激光治疗后腔内肿瘤复发。本文讨论了旨在解除恶性局部气道梗阻的各种方法,重点是最近开发的硅酮支架。

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