Arnott S, Winter W T
Fed Proc. 1977 Jan;36(1):73-8.
Among the mucopolysaccharides, similarities of chemical constitution are manifested in the similar molecular conformations that can be assumed by most of them. The differences, however, result in a preference for particular conformations. Small amounts of one glycosaminoglycan in a mixture can change the conformational preference of the major component. Advances in the techniques of fiber diffraction analysis allow us to visualize the roles of water and ions in some of these structures and to rationalize the strikingly different effects produced by Ca2+ and Na+ in hyaluronate systems, for example.
在黏多糖中，化学组成的相似性体现在它们大多数能够呈现出的相似分子构象上。然而，这些差异导致了对特定构象的偏好。混合物中少量的一种糖胺聚糖能够改变主要成分的构象偏好。例如，纤维衍射分析技术的进步使我们能够直观地看到水和离子在其中一些结构中的作用，并合理解释钙离子（Ca2+）和钠离子（Na+）在透明质酸系统中产生的显著不同的效应。
