Nixon R A
Mailman Research Center, McLean Hospital, Belmont, Massachusetts 02178-9106.
Curr Opin Cell Biol. 1992 Feb;4(1):8-14. doi: 10.1016/0955-0674(92)90052-e.
New studies provide further evidence that the neuronal cytoskeleton is the product of a dynamic interplay between axonal transport processes and locally regulated assembly mechanisms. These data confirm that the axonal cytoskeleton in mammalian systems is largely stationary and is maintained by a smaller pool of moving subunits or polymers. Slow axonal transport in certain lower species, however, may exhibit quite different features.
新的研究提供了进一步的证据,表明神经元细胞骨架是轴突运输过程和局部调节组装机制之间动态相互作用的产物。这些数据证实,哺乳动物系统中的轴突细胞骨架在很大程度上是静止的,由较少的移动亚基或聚合物池维持。然而,某些低等物种中的轴突慢速运输可能表现出截然不同的特征。