Yanes C, Monzon-Mayor M, de Barry J, Gombos G
Departamento de M. y Biologia Celular, Facultad de Biologia, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
Anat Embryol (Berl). 1992;185(5):475-87. doi: 10.1007/BF00174085.
We have studied in the telencephalon and mesencephalon of the lizard Gallotia galloti the localization and the chronology of appearance of the immunoreactivity due to the presence of a myelin-specific protein: the Myelin Basic Protein (MBP). MBP-like immunoreactivity was present with different degrees of intensity in many nerve fibers (isolated, in tracts and in commissurae) and it was apparently more abundant in mesencephalon. During ontogeny the earliest MBP-like immunoreactivity was detected at E.36 in few tracts in mesencephalon and appeared at E.40 in telencephalon, proceeding caudo-rostrally and from the ventral (basal) to the dorsal (alar) regions. Accumulation of MBP continued after hatching. Oligodendrocyte cell bodies were not immunopositive, not even at the youngest ages studied.
我们研究了加洛蒂蜥蜴（Gallotia galloti）端脑和中脑中因髓鞘特异性蛋白——髓鞘碱性蛋白（MBP）的存在而产生的免疫反应性的定位和出现时间顺序。MBP样免疫反应性在许多神经纤维（孤立的、束状的和连合处的）中以不同强度存在，且在中脑中显然更为丰富。在个体发育过程中，最早在胚胎第36天在中脑的少数束中检测到MBP样免疫反应性，在胚胎第40天出现在端脑中，从尾端向头端、从腹侧（基底）向背侧（翼）区域发展。孵化后MBP继续积累。少突胶质细胞胞体没有免疫阳性反应，即使在研究的最年幼阶段也是如此。
