银质沉着病小鼠的免疫复合物肾小球疾病
Immmune complex glomerular disease in argyric mice.
作者信息
Hunt J S, McGiven A R, Day W A
出版信息
Pathology. 1976 Jul;8(3):205-10. doi: 10.3109/00313027609059001.
PMID:137381
Abstract
A mesangiopathic glomerulonephritis with prominent mesangial immunoglobulin deposits was induced in mice by single or multiple intraperitoneal injections of bovine serum albumin. The silver-labelled basement membrane in mice which had ingested 6mM silver nitrate in drinking water proved a useful marker indetermining that the immune deposits were on the intracapillary aspect of the basement membrane.
摘要
通过单次或多次腹腔注射牛血清白蛋白，在小鼠中诱发了一种伴有显著系膜免疫球蛋白沉积的系膜病性肾小球肾炎。给饮用含6mM硝酸银水的小鼠进行银标记基底膜染色，结果证明这是一种有用的标记物，可确定免疫沉积物位于基底膜的毛细血管内侧面。
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