Rühlmann C, Koksch M, Kuklinski B
Abteilung Kardiologie/Angiologie, Universität Leipzig.
Z Gesamte Inn Med. 1992 Jan;47(1):6-11.
Three male patients with hyperlipidaemia were given daily infusions of dextran over a period of 10 days. Plasma levels of total cholesterol, LDL and HDL cholesterol, apolipoprotein B and AI and triglycerides were analysed after the infusion of dextrans different in dose and molecular size. Dextrans caused alterations of some plasma lipids and lipoproteins exceeding the haemodilution effect. The degree of lipid lowering depends on the volume and molecular size of the administered dextran.
三名高脂血症男性患者在10天内每日输注右旋糖酐。在输注不同剂量和分子大小的右旋糖酐后，分析了血浆总胆固醇、低密度脂蛋白和高密度脂蛋白胆固醇、载脂蛋白B和AI以及甘油三酯的水平。右旋糖酐引起的一些血浆脂质和脂蛋白的改变超过了血液稀释效应。降脂程度取决于所给予右旋糖酐的体积和分子大小。
