正常前列腺、前列腺癌及良性前列腺增生的体积：与前列腺特异性抗原的相关性在临床上是否有用？

Volume of normal prostate, of prostate cancer, and of benign prostatic hyperplasia: are correlations with prostate specific antigen clinically useful?

作者信息

Clements R, Penney M D, Etherington R J, Griffiths G J, Hughes H, Peeling W B

机构信息

Department of Radiology, St. Woolos Hospital, Newport, Gwent, UK.

出版信息

Prostate Suppl. 1992;4:51-7. doi: 10.1002/pros.2990210508.

DOI:10.1002/pros.2990210508

PMID:1374178

Abstract

This retrospective study correlated prostate volume, determined by transrectal ultrasonography, with serum prostate specific antigen (PSA), by Deming regression analysis, in patients with confirmed benign prostatic hyperplasia (BPH) and patients with non-metastatic (M0) or metastatic (M1) prostate cancer. In BPH, a highly significant correlation was found between log10[PSA] and prostate volume. When this PSA/volume regression pattern for BPH was used as a reference standard, all 17 patients with M1 prostate cancer and 83% of the 23 patients with M0 disease were discriminated from BPH.

摘要

本回顾性研究通过Deming回归分析，在确诊为良性前列腺增生（BPH）的患者以及非转移性（M0）或转移性（M1）前列腺癌患者中，将经直肠超声测定的前列腺体积与血清前列腺特异性抗原（PSA）进行关联分析。在BPH患者中，发现log10[PSA]与前列腺体积之间存在高度显著的相关性。当将这种BPH的PSA/体积回归模式用作参考标准时，所有17例M1前列腺癌患者和23例M0疾病患者中的83%被鉴别为非BPH。