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钕钇铝石榴石激光对结直肠癌的姑息治疗效果不佳。

Poor palliation of colorectal malignancy with the neodymium yttrium-aluminium-garnet laser.

作者信息

Bright N, Hale P, Mason R

机构信息

Department of Surgery, United Medical School, Guy's Hospital, London, UK.

出版信息

Br J Surg. 1992 Apr;79(4):308-9. doi: 10.1002/bjs.1800790407.

DOI:10.1002/bjs.1800790407
PMID:1374279
Abstract

The neodymium yttrium-aluminium-garnet (NdYAG) laser was used to palliate the symptoms of 38 patients with rectal carcinoma unsuitable for radical surgery. All patients with small tumours (n = 6) reported resolution of their symptoms. In contrast, those with large tumours frequently showed little improvement (n = 18) and alternative surgical management was necessary in 12 patients. The overall early mortality rate (less than 1 month after first treatment) was 21 per cent. The NdYAG laser offers good palliation and may even cure small colorectal tumours in patients who are unsuitable for surgery. For large circumferential tumours, those associated with obstruction and those close to or involving the anal sphincters, however, the results are poor and better symptom control may be achieved by other means.

摘要

钕钇铝石榴石(NdYAG)激光用于缓解38例不宜行根治性手术的直肠癌患者的症状。所有小肿瘤患者(n = 6)症状均得到缓解。相比之下,大肿瘤患者症状改善不明显(n = 18),12例患者需要采取其他手术治疗。总体早期死亡率(首次治疗后不到1个月)为21%。NdYAG激光能有效缓解症状,甚至可能治愈不宜手术的小的结直肠肿瘤。然而,对于大的环形肿瘤、伴有梗阻的肿瘤以及靠近或累及肛门括约肌的肿瘤,效果较差,通过其他方法可能能更好地控制症状。

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Poor palliation of colorectal malignancy with the neodymium yttrium-aluminium-garnet laser.钕钇铝石榴石激光对结直肠癌的姑息治疗效果不佳。
Br J Surg. 1992 Apr;79(4):308-9. doi: 10.1002/bjs.1800790407.
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