Li Y W, Ding Z Q, Wesselingh S L, Blessing W W
Department of Medicine, Flinders University of South Australia.
Brain Res. 1992 Feb 21;573(1):147-52. doi: 10.1016/0006-8993(92)90124-r.
We mapped sympathetic renal preganglionic neurons in the rabbit spinal cord using Herpes simplex virus retrograde transneuronal tracing after application of the virus to the renal nerve. Virus-positive neurons were found in the spinal cord from T7 to L2, principally in the ipsilateral intermediolateral cell column. Renal and adrenal preganglionic neurons are largely separate populations. Extensive nonspecific spread of virus from infected cells to neighboring neurons does not appear to occur.
我们在将单纯疱疹病毒应用于肾神经后，利用单纯疱疹病毒逆行跨神经元示踪技术，在兔脊髓中定位了交感肾节前神经元。在T7至L2脊髓节段发现了病毒阳性神经元，主要位于同侧中间外侧细胞柱。肾和肾上腺节前神经元在很大程度上是不同的群体。未发现病毒从受感染细胞广泛非特异性扩散至邻近神经元的现象。
