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孕期用药。药物对胎儿及新生儿的影响。

Drugs in pregnancy. Their effects on the fetus and newborn.

作者信息

SANDBERG D H

出版信息

Calif Med. 1961 May;94(5):287-91.

Abstract

In considering drug therapy for pregnant women, it must be borne in mind that almost all chemical compounds in use as therapeutic agents pass from the maternal to the fetal circulation through the placenta. These drugs can produce a wide range of harmful effects on the fetus and neonatal infant. The effects of some substances for which we have data reflecting a deleterious effect are listed. It is suggested that in the future more caution be exercised in using drugs during pregnancy and that in histories, both obstetrical and pediatric, any therapy given to the mother during gestation be recorded in detail.

摘要

在考虑对孕妇进行药物治疗时,必须牢记,几乎所有用作治疗药物的化合物都会通过胎盘从母体循环进入胎儿循环。这些药物会对胎儿和新生儿产生广泛的有害影响。我们列出了一些有数据表明存在有害影响的物质的影响。建议未来在孕期用药时要更加谨慎,并且在产科和儿科病史中,详细记录孕期给予母亲的任何治疗。

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本文引用的文献

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Some contra-indications to the use of chlorpromazine (with particular reference to obstetric analgesia and anaesthesia).
J Obstet Gynaecol Br Emp. 1959 Feb;66(1):91-8. doi: 10.1111/j.1471-0528.1959.tb01139.x.
10
Narcotic withdrawal symptoms in newborn infants.新生儿的麻醉药戒断症状。
J Am Med Assoc. 1958 Oct 25;168(8):1008-10. doi: 10.1001/jama.1958.63000080001007.

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