Sukhar' V V, Uraleva V S
Mikrobiol Zh (1978). 1992 Mar-Apr;54(2):42-6.
A new envelope antigen C, specific for virulent strains of Francisella tularensis, was revealed by immunodiffusion analysis. In contrast to antigens A and P this antigen is common for Francisella and Brucella. C-antigenic lipid fraction was obtained by chloroform-ethanol (1:1) extraction of bacterial slime. This fraction contained carbohydrates (31.6%) without proteins and detected by TLC glycolipid, which proved glycolipid nature of C-antigen. Introduction of C-fraction or alive F. tularensis resulted in accumulation of C. precipitins in blood serum.
通过免疫扩散分析发现了一种新的包膜抗原C，它对土拉弗朗西斯菌的强毒株具有特异性。与抗原A和P不同，这种抗原在弗朗西斯菌和布鲁氏菌中是常见的。C抗原脂质部分是通过用氯仿 - 乙醇（1:1）提取细菌黏液获得的。该部分含有碳水化合物（31.6%），不含蛋白质，通过薄层层析糖脂检测到，这证明了C抗原的糖脂性质。引入C部分或活的土拉弗朗西斯菌会导致血清中C沉淀素的积累。
