Wässle H, Grünert U, Cook N J, Molday R S
Max-Planck-Institut für Hirnforschung, Frankfurt am Main, F.R.G.
Neurosci Lett. 1992 Jan 6;134(2):199-202. doi: 10.1016/0304-3940(92)90516-a.
It has recently been suggested (Nature, 346 (1990) 269-271) that ON-bipolar cells express the same biochemical cascade and guanosine 3',5'-cyclic monophosphate (cGMP)-gated cation channel as rod outer segments. An antibody directed against the cGMP-gated channel of bovine rod outer segments was applied to cryostat sections of rat and cat retinae. No immunocytochemical labelling was found in bipolar cells. Therefore, if those cells express a cGMP-gated channel, it must be immunologically different to the 63 kDa protein constituting the cGMP-gated channel of the outer segment.
最近有人提出（《自然》，346 (1990) 269 - 271），ON - 双极细胞表达与视杆细胞外段相同的生化级联反应和鸟苷3',5'-环磷酸（cGMP）门控阳离子通道。将一种针对牛视杆细胞外段cGMP门控通道的抗体应用于大鼠和猫视网膜的低温切片。在双极细胞中未发现免疫细胞化学标记。因此，如果这些细胞表达cGMP门控通道，那么它在免疫学上必然与构成外段cGMP门控通道的63 kDa蛋白质不同。
