Van der Meij W, Van Huffelen A C, Wieneke G H, Willemse J
Department of Clinical Neurophysiology, University Hospital Utrecht, The Netherlands.
Electroencephalogr Clin Neurophysiol. 1992 Jun;82(6):408-14. doi: 10.1016/0013-4694(92)90045-j.
Sequential topographic mapping was performed to differentiate "epileptic" from "non-epileptic" rolandic spikes. Twenty-four children without any indication of organic brain lesion were divided into a group with epilepsy and a group without epilepsy. The group with epilepsy was subdivided into "classical BECT" (benign focal epilepsy of childhood with centro-temporal spikes) and "non-classical BECT." Sequential mapping of the rolandic spikes revealed two different topographic patterns: a pattern of stationary potential fields and a pattern of non-stationary potential fields. The topographic pattern of stationary potential fields was morphologically represented by a single spike-and-wave complex whereas that of non-stationary potential fields was morphologically represented by a "double" spike-and-wave complex. Among the non-stationary topographic patterns represented by a "double" spike, one specific sequence of changes of potential fields was found. This sequence started with a dipolar field, with the negative pole in the frontal region and the positive pole in the centro-temporal region, morphologically represented by the small first spike of the "double" spike-and-wave complex. This dipolar field, changes to a unipolar or dipolar field, with a negative potential field in the centro-temporal region and, sometimes, a simultaneous positive potential field in the frontal region, morphologically represented by the prominent rolandic spike. This characteristic pattern was found to be significantly related to classical BECT.
进行序列地形图绘制以区分“癫痫性”与“非癫痫性”中央颞区棘波。24名无任何器质性脑损伤迹象的儿童被分为癫痫组和非癫痫组。癫痫组又细分为“典型儿童良性中央颞区棘波灶性癫痫（BECT）”和“非典型BECT”。中央颞区棘波的序列地形图显示出两种不同的地形模式：静止电位场模式和非静止电位场模式。静止电位场的地形模式在形态上由单个棘慢复合波表示，而非静止电位场的地形模式在形态上由“双”棘慢复合波表示。在由“双”棘波表示的非静止地形模式中，发现了一种特定的电位场变化序列。该序列始于一个偶极场，负极在额叶区域，正极在中央颞区，在形态上由“双”棘慢复合波的第一个小棘波表示。这个偶极场转变为单极或偶极场，中央颞区为负电位场，有时额叶区域同时存在正电位场，在形态上由突出的中央颞区棘波表示。发现这种特征模式与典型BECT显著相关。
