Percutaneous, ultrasound-directed ablation of ectopic pregnancy with methotrexate. A report of three cases.

The early diagnosis of unruptured ectopic pregnancy has been facilitated by the availability of high-resolution ultrasound and sensitive quantitative assays for beta-human chorionic gonadotropin. Nonsurgical treatment of selected patients has been advocated. Three patients with fairly advanced unruptured ectopic pregnancies were treated with ablation with methotrexate using an ultrasound-directed, percutaneous technique. That approach appears to be reasonable and safe in selected patients, though the subsequent reproductive performance is unknown.