Grimalt R, Gelmetti C
First Department of Dermatology, University of Milan, IRCCS, Ospedale Maggiore, Italy.
Pediatr Dermatol. 1992 Jun;9(2):98-102. doi: 10.1111/j.1525-1470.1992.tb01222.x.
A 6-year-old Caucasian girl had dozens of asymptomatic, flesh-colored, 2- to 5-mm eruptive vellus hair cysts. These papules on the buttocks, thighs, and groin increased in number for three months. Histologic examination revealed poorly defined, keratin-filled cysts in the upper middermis, containing numerous transversely or obliquely cut portions of vellus hair. The histopathologic differential diagnosis with other epithelial cysts containing hair shafts is debated, and new clinical differential diagnoses are proposed. Review of the literature suggests that eruptive vellus hair cyst is not a rare disorder, but its frequency is probably underestimated due to paucity of symptoms. Nevertheless, the clinical relevance of some of the differential diagnoses should convince clinicians to obtain histologic confirmation.
一名6岁的白种女孩有数十个无症状的、肤色的、2至5毫米大小的发疹性毳毛囊肿。这些丘疹出现在臀部、大腿和腹股沟,数量在三个月内不断增加。组织学检查显示,在中上部真皮层有边界不清、充满角蛋白的囊肿,其中包含许多横向或斜向切断的毳毛部分。与其他含有毛干的上皮囊肿的组织病理学鉴别诊断存在争议,并提出了新的临床鉴别诊断。文献回顾表明,发疹性毳毛囊肿并非罕见疾病,但由于症状较少,其发病率可能被低估。然而,一些鉴别诊断的临床相关性应促使临床医生获得组织学确诊。