MERZ T, SWANSON C P, COHN N S
Science. 1961 Mar 10;133(3454):703-5. doi: 10.1126/science.133.3454.703.
The results of combination treatments of the roots of Vicia faba with certain radiomimetic compounds (8-ethoxycaffeine, maleic hydrazide, beta-propiolactone, potassium cyanide) and x-ray as well as combination treatments of certain radiomimetic compounds with one another were observed to determine whether interaction will occur between chromosomal breaks induced by different agents. Interaction was observed between breaks induced by x-rays and all of the breaks induced by chemicals but not between breaks induced by any two chemicals. The results are discussed in terms of possible breakage bond differences and the effects of temporal and spatial differences in breaks induced by different agents.
研究观察了蚕豆根与某些拟辐射化合物（8-乙氧基咖啡因、马来酰肼、β-丙内酯、氰化钾）及X射线的联合处理结果，以及某些拟辐射化合物相互之间的联合处理结果，以确定不同因素诱导的染色体断裂之间是否会发生相互作用。观察到X射线诱导的断裂与所有化学物质诱导的断裂之间存在相互作用，但任意两种化学物质诱导的断裂之间未观察到相互作用。根据可能的断裂键差异以及不同因素诱导的断裂在时间和空间上的差异效应，对结果进行了讨论。
