Viksman M E, Maianskiĭ D N
Arkh Patol. 1976;38(12):46-51.
Morphological and histochemical characteristics of the spleen in the systemic and locally induced in the spleen transplant host reaction were compared. In both forms there were observed infiltration of the organ with macrophages and pyroninophilial blasts characterized by a high level of the activity of enzymes of lysosomas and a hexosemonophosphate cycle. In the process of interaction between genetically heterogenous mononuclear cells the disturbance of enzymatic processes in them and in the adjacent cellular elements took place, and susequently they underwent necrosis. Most frequently this process was observed in lymphoid follicles. The destructive component in the spleen tissue was more pronounced in the systemic transplant against host reaction.
比较了在全身和局部诱导的脾移植宿主反应中脾脏的形态学和组织化学特征。在这两种形式中，均观察到器官中有巨噬细胞和嗜派洛宁细胞的浸润，其特征是溶酶体酶和磷酸己糖循环的活性水平较高。在遗传异质单核细胞之间的相互作用过程中，它们以及相邻细胞成分中的酶促过程发生紊乱，随后它们发生坏死。最常在此过程在淋巴滤泡中观察到。在全身移植抗宿主反应中，脾组织中的破坏成分更为明显。
