BURTON P, HAMMOND E M, HARPER A A, HOWAT H T, SCOTT J E, VARLEY H
Gut. 1960 Jun;1(2):125-39. doi: 10.1136/gut.1.2.125.
A simple evocative test has been used to study pancreatic function. Serial estimations of amylase and lipase in blood serum are made at intervals up to six hours and again at 24 hours after injecting intravenously standard doses of secretin and pancreozymin. The results of 213 tests on a normal group, in pancreatic disease, in biliary and hepatic diseases have been analysed and compared with the results of duodenal intubation and an oral glucose tolerance test. A combined evocative test and oral glucose tolerance test provide evidence of pancreatic dysfunction in the majority of cases of cancer of the pancreas and chronic pancreatitis. The conditions of the test are described and the pathological lesions in which false positive evocative tests may be found are indicated. The simple evocative test provides the earliest biochemical evidence of pancreatic disease in some patients with cancer of the pancreas and chronic pancreatitis.
一种简单的激发试验已被用于研究胰腺功能。静脉注射标准剂量的促胰液素和胰酶泌素后，每隔一定时间直至6小时，以及在24小时时，对血清淀粉酶和脂肪酶进行系列测定。对正常组、胰腺疾病组、胆道和肝脏疾病组的213次试验结果进行了分析，并与十二指肠插管和口服葡萄糖耐量试验的结果进行了比较。联合激发试验和口服葡萄糖耐量试验在大多数胰腺癌和慢性胰腺炎病例中提供了胰腺功能障碍的证据。描述了试验条件，并指出了可能出现假阳性激发试验的病理病变。这种简单的激发试验在一些胰腺癌和慢性胰腺炎患者中提供了胰腺疾病最早的生化证据。
