Andria M L, Barsh G S, Levy S
Department of Medicine/Oncology, Stanford University School of Medicine, CA.
Biochem Biophys Res Commun. 1992 Aug 14;186(3):1201-6. doi: 10.1016/s0006-291x(05)81533-5.
TAPA-1 is a member of a new family of evolutionarily conserved transmembrane proteins which may be involved in regulation of cell growth and/or cell signalling. We have examined the temporal pattern of TAPA-1 RNA expression during mouse development. Using a sensitive reverse transcription/polymerase chain reaction assay, we show that TAPA-1 RNA is present in oocytes, fertilized eggs and cleavage stage embryos.
TAPA-1是一个新的进化保守跨膜蛋白家族的成员,可能参与细胞生长和/或细胞信号传导的调节。我们研究了小鼠发育过程中TAPA-1 RNA表达的时间模式。使用灵敏的逆转录/聚合酶链反应分析,我们发现TAPA-1 RNA存在于卵母细胞、受精卵和卵裂期胚胎中。