Dittrich H, Kutchan T M, Zenk M H
Lehrstuhl für Pharmazeutische Biologie, Universität München, Germany.
FEBS Lett. 1992 Aug 31;309(1):33-6. doi: 10.1016/0014-5793(92)80733-w.
The pentacyclic biosynthetic precursor of jasmonic acid, 12-oxo-phytodienoic acid, was found to induce synthesis of the major flavonoid, apiin, in cell suspension cultures of Petroselinum crispum. The accumulation of apiin was preceded by an increase in the relative levels of poly (A)+ RNAs that code for the flavonoid biosynthetic enzymes phenylalanine ammonia lyase, 4-coumarate:CoA ligase and chalcone synthase, Poly (A)+ RNAs reached maximal levels at approximately 4-6 h after the addition of elicitor while flavonoids continued to accumulate in the cultures for at least 6 days. 12-Oxo-phytodienoic acid is the first pentacyclic precursor in the jasmonic acid biosynthetic chain which functions as a signal transducer for phytoalexin induction.
茉莉酸的五环生物合成前体12-氧代植物二烯酸，被发现可在皱叶欧芹的细胞悬浮培养物中诱导主要类黄酮芹菜素的合成。芹菜素的积累之前，编码类黄酮生物合成酶苯丙氨酸解氨酶、4-香豆酸：辅酶A连接酶和查尔酮合酶的多聚腺苷酸（poly (A)+）RNA的相对水平有所增加。添加诱导子后约4-6小时，多聚腺苷酸（poly (A)+）RNA达到最大水平，而类黄酮在培养物中持续积累至少6天。12-氧代植物二烯酸是茉莉酸生物合成链中的首个五环前体，它作为诱导植保素的信号转导分子发挥作用。
