极早产儿短暂性甲状腺素血症与发育迟缓相关
Transient hypothyroxinaemia associated with developmental delay in very preterm infants.
作者信息
Meijer W J, Verloove-Vanhorick S P, Brand R, van den Brande J L
机构信息
TNO Institute of Preventive Health Care, Leiden, The Netherlands.
出版信息
Arch Dis Child. 1992 Jul;67(7):944-7. doi: 10.1136/adc.67.7.944.
Abstract
In 563 surviving very preterm (less than 32 weeks gestational age) and/or very low birthweight (less than 1500 g) infants the relationship between neonatal thyroxine concentration and psychomotor development at 2 years of age (corrected for preterm birth) was studied. A significant association was found between low neonatal thyroxine concentration and a negative score on the three milestones of development. These findings do not support the view that transient hypothyroxinaemia in preterm infants is harmless.
摘要
在563名存活的极早产儿（胎龄小于32周）和/或极低出生体重儿（出生体重小于1500克）中，研究了新生儿甲状腺素浓度与2岁时（校正早产因素后）精神运动发育之间的关系。研究发现，新生儿甲状腺素浓度低与发育的三个里程碑得分呈负相关。这些发现不支持早产儿短暂性甲状腺素血症无害的观点。
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