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[美西律对心肌梗死后患者室性心律失常的长期治疗]

[Long-term mexiletine treatment of ventricular arrhythmia in patients after myocardial infarction].

作者信息

Drazkiewicz U, Petelenz T, Axenti I, Olszowy Z

机构信息

III Kliniki Kardiologii Sl. A.M., Katowicach.

出版信息

Pol Arch Med Wewn. 1992 Mar;87(3):157-67.

PMID:1381822
Abstract

Eighty two patients with ventricular extrasystole (VES) after myocardial infarction had been treated with antiarrhythmic drugs in the half (41 patients) with mexiletine (M) and in the half (41 patients) with other ones. The mortality rate in the M-group was twice time lower than in the other, however this difference was statistically not significant. M was mostly effective in VES of III and IVb degree after Lown's classification and did not cause any deterioration of the left ventricle function.

摘要

82例心肌梗死后室性早搏(VES)患者,一半(41例)用美西律(M)治疗,另一半(41例)用其他药物治疗。M组的死亡率比另一组低两倍,但这种差异在统计学上并不显著。根据洛恩分类法,M对III级和IVb级室性早搏最有效,且不会导致左心室功能恶化。

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1
[Long-term mexiletine treatment of ventricular arrhythmia in patients after myocardial infarction].[美西律对心肌梗死后患者室性心律失常的长期治疗]
Pol Arch Med Wewn. 1992 Mar;87(3):157-67.
2
[Evaluation of the efficiency of mexiletine in ventricular extrasystole in the post-infarct stage].[美西律对心肌梗死后室性期前收缩疗效的评估]
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[Mexiletine therapy of ventricular extrasystoles in the acute phase of myocardial infarction].
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Signal-averaged ECG in prediction of the short-term suppression of ventricular premature beats by Mexiletine.信号平均心电图在预测美西律对室性早搏的短期抑制作用中的应用
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[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)].美西律、普罗帕酮和氟卡尼对室性早搏的抗心律失常疗效。心肌梗死后患者的比较研究(作者译)
Z Kardiol. 1982 May;71(5):340-9.
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