Drazkiewicz U, Petelenz T, Axenti I, Olszowy Z
III Kliniki Kardiologii Sl. A.M., Katowicach.
Pol Arch Med Wewn. 1992 Mar;87(3):157-67.
Eighty two patients with ventricular extrasystole (VES) after myocardial infarction had been treated with antiarrhythmic drugs in the half (41 patients) with mexiletine (M) and in the half (41 patients) with other ones. The mortality rate in the M-group was twice time lower than in the other, however this difference was statistically not significant. M was mostly effective in VES of III and IVb degree after Lown's classification and did not cause any deterioration of the left ventricle function.
82例心肌梗死后室性早搏(VES)患者,一半(41例)用美西律(M)治疗,另一半(41例)用其他药物治疗。M组的死亡率比另一组低两倍,但这种差异在统计学上并不显著。根据洛恩分类法,M对III级和IVb级室性早搏最有效,且不会导致左心室功能恶化。