肉碱在0.7%氯化钠溶液中无法预防青蛙横纹肌抽搐。
The ineffectiveness of carnitine preventing the twitchings of striated frog muscle in 0.7 per cent sodium chloride solution.
作者信息
FRIEBEL H
出版信息
Br J Pharmacol Chemother. 1959 Dec;14(4):420-2. doi: 10.1111/j.1476-5381.1959.tb00945.x.
Abstract
The spontaneous twitchings of isolated frog sartorius muscles in 0.7% NaCl solution have been studied. Addition of 1 mg./ml. of (+/-)-carnitine hydrochloride, or of (+/-)-carnitine base, to the bath fluid had no influence on the spontaneous activity of the muscles, their excitability or their ability to liberate potassium. This indicates that carnitine is not a natural inhibitor of striated frog muscle. Fluids enriched with potassium either from twitching muscle or by addition of KCl inhibited the activity of muscles reversibly.
摘要
对分离的青蛙缝匠肌在0.7%氯化钠溶液中的自发抽搐进行了研究。向浴液中添加1毫克/毫升的（±）-盐酸肉碱或（±）-肉碱碱，对肌肉的自发活动、兴奋性或释放钾的能力没有影响。这表明肉碱不是青蛙横纹肌的天然抑制剂。富含钾的液体，无论是来自抽搐的肌肉还是通过添加氯化钾，都能可逆地抑制肌肉的活动。
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The ineffectiveness of carnitine preventing the twitchings of striated frog muscle in 0.7 per cent sodium chloride solution.肉碱在0.7%氯化钠溶液中无法预防青蛙横纹肌抽搐。
Br J Pharmacol Chemother. 1959 Dec;14(4):420-2. doi: 10.1111/j.1476-5381.1959.tb00945.x.
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本文引用的文献
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