GROSSMAN S P
Science. 1960 Jul 29;132(3422):301-2. doi: 10.1126/science.132.3422.301.
A double cannula system, allowing repeated stimulation of central structures with crystalline chemicals, was developed. This technique was employed to study the effects of adrenergic and cholinergic stimulation of the lateral hypothalamus of rats. Drug-specific effects on the feeding and drinking mechanisms, respectively, were observed.
开发了一种双套管系统,该系统允许用结晶化学物质重复刺激中枢结构。采用该技术研究对大鼠下丘脑外侧进行肾上腺素能和胆碱能刺激的效果。分别观察到了药物对摄食和饮水机制的特异性作用。