大鼠脑刺激电流强度的自我调节

Self-regulation of brain-stimulating current intensity in the rat.

作者信息

STEIN L, RAY O S

出版信息

Science. 1959 Sep 4;130(3375):570-2. doi: 10.1126/science.130.3375.570.

DOI:10.1126/science.130.3375.570

Abstract

A modification of the self-stimulation technique of Olds enabled rats to regulate and maintain at a preferred level the amount of brain-stimulating current they received as reinforcement for lever pressing. The method used two levers to deliver brief brain shocks: each response at one lever increased the current intensity a small step and each response at the other lowered it one step.

摘要

奥兹自我刺激技术的一种改进方法能使大鼠将它们作为按压杠杆的强化物所接受的脑刺激电流的量调节并维持在一个偏好水平。该方法使用两个杠杆来传递短暂的脑部电击：在一个杠杆上的每次反应会使电流强度小幅增加一步，而在另一个杠杆上的每次反应会使其降低一步。