播散性生殖细胞癌强化化疗期间艰难梭菌腹泻的高发生率。
High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer.
作者信息
Nielsen H, Daugaard G, Tvede M, Bruun B
机构信息
Department of Clinical Microbiology, Rigshopitalet, Copenhagen, Denmark.
出版信息
Br J Cancer. 1992 Oct;66(4):666-7. doi: 10.1038/bjc.1992.334.
Abstract
A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients.
摘要
对25例接受强化化疗的播散性生殖细胞癌患者进行了一项关于治疗相关性腹泻病因的前瞻性、连续性研究。在45%的腹泻病例中分离出艰难梭菌，这使得该菌成为这群免疫功能低下患者发生具有临床意义腹泻的最重要细菌病原体。
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