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来自几个门的海洋和陆地无脊椎动物中神经元的喹吖因染色以及嘌呤核苷和核苷酸的活性。

Quinacrine-staining of neurones, and activity of purine nucleosides and nucleotides in marine and terrestrial invertebrates from several phyla.

作者信息

Knight G E, Hoyle C H, Burnstock G

机构信息

Department of Anatomy and Developmental Biology, University College London.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Jun;102(2):305-14. doi: 10.1016/0742-8413(92)90116-o.

DOI:10.1016/0742-8413(92)90116-o
PMID:1385035
Abstract
  1. The acridine derivative quinacrine was used to stain nerve fibres in internal organs of 17 species of marine and terrestrial invertebrates from seven different phyla. 2. The majority of preparations showed quinacrine-stained nerve fibres. There was a degree of variation, ranging from a dense network of nerve bundles to single fibres. Quinacrine-positive nerve cell bodies were also observed in some ganglia. 3. Pharmacological experiments were performed on a variety of isolated tissues from the different marine and terrestrial groups, in order to ascertain their sensitivity to adenine nucleosides and nucleotides. 4. Correlation is drawn between the ability of neurones within a tissue to bind quinacrine, and the ability of that tissue to respond to applied adenine nucleosides and nucleotides.
摘要
  1. 吖啶衍生物喹吖因被用于对来自七个不同门的17种海洋和陆地无脊椎动物的内脏神经纤维进行染色。2. 大多数标本显示出喹吖因染色的神经纤维。存在一定程度的差异,从密集的神经束网络到单根纤维不等。在一些神经节中也观察到喹吖因阳性的神经细胞体。3. 对来自不同海洋和陆地类群的多种分离组织进行了药理学实验,以确定它们对腺嘌呤核苷和核苷酸的敏感性。4. 在组织内神经元结合喹吖因的能力与该组织对施加的腺嘌呤核苷和核苷酸的反应能力之间建立了相关性。

相似文献

1
Quinacrine-staining of neurones, and activity of purine nucleosides and nucleotides in marine and terrestrial invertebrates from several phyla.来自几个门的海洋和陆地无脊椎动物中神经元的喹吖因染色以及嘌呤核苷和核苷酸的活性。
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Jun;102(2):305-14. doi: 10.1016/0742-8413(92)90116-o.
2
Fluorescence-microscopical demonstration of a population of gastro-intestinal nerve fibres with a selective affinity for quinacrine.荧光显微镜下显示一群对喹吖因具有选择性亲和力的胃肠神经纤维。
Cell Tissue Res. 1976 Sep 1;171(4):407-23. doi: 10.1007/BF00220234.
3
Stimulation of astrocyte proliferation by purine and pyrimidine nucleotides and nucleosides.嘌呤和嘧啶核苷酸及核苷对星形胶质细胞增殖的刺激作用。
Glia. 1993 Feb;7(2):176-82. doi: 10.1002/glia.440070207.
4
Analysis of radioactive and nonradioactive purine bases, purine nucleosides and purine nucleotides by high-speed chromatography on a single column.通过单柱高速色谱法分析放射性和非放射性嘌呤碱、嘌呤核苷及嘌呤核苷酸。
Monogr Hum Genet. 1978;10:127-34. doi: 10.1159/000401581.
5
Effect of purine nucleosides and nucleotides on the in vivo radiation response of normal tissue in the rat.嘌呤核苷和核苷酸对大鼠正常组织体内辐射反应的影响。
Int J Radiat Oncol Biol Phys. 1981 Mar;7(3):365-9. doi: 10.1016/0360-3016(81)90110-3.
6
Analysis of radioactive and nonradioactive purine bases, nucleosides, and nucleotides by high-speed chromatography on a single column.
Anal Biochem. 1978 May;86(1):65-77. doi: 10.1016/0003-2697(78)90319-6.
7
High-performance liquid chromatography analysis of purine nucleosides in human gingival crevicular fluid.
Arch Oral Biol. 1984;29(8):607-10. doi: 10.1016/0003-9969(84)90129-8.
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The actions of adenosine and various nucleosides and nucleotides on the isolated toad spinal cord.腺苷及各种核苷和核苷酸对离体蟾蜍脊髓的作用。
Gen Pharmacol. 1978;9(4):239-47. doi: 10.1016/0306-3623(78)90043-5.
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Purine nucleoside and nucleotide interactions on normal and subsensitive alpha adrenoreceptor responsiveness in guinea-pig vas deferens.嘌呤核苷和核苷酸对豚鼠输精管正常和亚敏感α肾上腺素能受体反应性的影响
J Pharmacol Exp Ther. 1978 Apr;205(1):104-17.
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Comparative studies of quinacrine-positive neurones in the myenteric plexus of stomach and intestine of guinea-pig, rabbit and rat.豚鼠、兔和大鼠胃及肠肌间神经丛中奎纳克林阳性神经元的比较研究。
Cell Tissue Res. 1981;221(1):93-107. doi: 10.1007/BF00216573.

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