Nersisian V M, Musaelian N O, Martirosian I G
Gematol Transfuziol. 1992 Feb;37(2):24-6.
Inv (1) antigen distribution was studied in 568 normal subjects and in 354 hematological patients in the Armenian population. Inv (1) antigen was detected in 16.7% of the normal Armenians studied. The incidence rate of Inv (1) factor does not depend on the distribution of phenotypes of ABO system, rhesus factor (D), and the sex of the subjects investigated. Inv (1) antigen incidence rate in patients with acute leukemia, chronic lymphocytic leukemia, iron deficiency anemia, lymphogranulomatosis, idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia was similar to that in the control, and only patients with chronic myeloid leukemia had significantly decreased levels of Inv (1) antigen: 6.8% as compared to 16.7% in the population.
对亚美尼亚人群中的568名正常受试者和354名血液病患者进行了Inv(1)抗原分布研究。在所研究的正常亚美尼亚人中,16.7%检测到Inv(1)抗原。Inv(1)因子的发生率不取决于ABO系统的表型分布、恒河猴因子(D)以及所研究受试者的性别。急性白血病、慢性淋巴细胞白血病、缺铁性贫血、淋巴肉芽肿病、特发性血小板减少性紫癜、自身免疫性溶血性贫血患者的Inv(1)抗原发生率与对照组相似,只有慢性髓性白血病患者的Inv(1)抗原水平显著降低:为6.8%,而人群中的发生率为16.7%。