Moore R J, Durbridge T C, McNeil P J, Parkinson I H, Need A G, Vernon-Roberts B
Division of Tissue Pathology, Institute of Medical and Veterinary Science, Adelaide, SA.
Aust N Z J Med. 1992 Jun;22(3):269-73. doi: 10.1111/j.1445-5994.1992.tb02124.x.
Histomorphometric measurements were made from iliac crest biopsies of 32 women with vertebral fractures and 37 women without fracture. All were post-menopausal Australian women who had presented with back pain to a hospital out-patient endocrinology clinic. Bone from the fracture cases was characterised by loss of individual trabecular elements, with the remaining trabeculae being spaced further apart than those in the non-fracture women (p less than 0.0001). This resulted in a significant decrease in trabecular bone volume (p less than 0.01). In addition osteoid surface was reduced (p less than 0.01). Dynamic parameters of bone turnover were not significantly different between the two groups. These data should be useful for the assessment of iliac bone histomorphometry in Australian post-menopausal women suspected of having osteoporosis.
对32名患有椎体骨折的女性和37名未发生骨折的女性进行了髂嵴活检的组织形态计量学测量。所有女性均为绝经后澳大利亚女性，她们因背痛前往医院门诊内分泌诊所就诊。骨折病例的骨骼特征是单个小梁骨成分缺失，其余小梁骨的间距比未骨折女性的小梁骨间距更大（p<0.0001）。这导致小梁骨体积显著减少（p<0.01）。此外，类骨质表面减少（p<0.01）。两组之间骨转换的动态参数没有显著差异。这些数据对于评估疑似患有骨质疏松症的澳大利亚绝经后女性的髂骨组织形态计量学应是有用的。
