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透析中心的乙型肝炎疫苗接种:优势与局限

Hepatitis B vaccination in dialysis centres: advantages and limits.

作者信息

Rapicetta M

机构信息

Department of Virology, Istituto Superiore di Sanità, Rome, Italy.

出版信息

Nephron. 1992;61(3):284-6. doi: 10.1159/000186906.

Abstract

A review is presented on the results achieved in HBV immunization of hemodialysis patients with aluminum-adsorbed, subunit plasma-derived and yeast-derived vaccines. The main host-related and immunization-related causes of low response are discussed. Various possibility to improve the vaccine performance through appropriate dosage and schedule, as well as immunopotentiating procedures are reported.

摘要

本文综述了使用铝吸附疫苗、亚单位血浆源性疫苗和酵母源性疫苗对血液透析患者进行乙肝病毒免疫接种所取得的成果。讨论了免疫反应低下的主要宿主相关因素和免疫相关因素。报告了通过适当的剂量和接种程序以及免疫增强程序来提高疫苗效果的各种可能性。

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