BLACKLIDGE B Y
Calif Med. 1961 Oct;95(4):219-23.
Hypernatremic dehydration is a fairly common and potentially very dangerous illness in infants and children. It occurs during the course of a wide variety of illnesses. Predisposing factors include central nervous system diseases, decreased fluid intake, increased fluid losses from hyperventilation, perspiring, diarrhea and emesis, increased aldosterone output (contributing to sodium retention), the infant's high obligatory renal water loss and the practice of feeding infants fluids with a comparatively high solute content. If the attending physician is aware of the predisposing factors and makes an early diagnosis and then rehydrates the patient slowly using solutions which contain some salt, the outcome will most likely be favorable. Even though the brain appears to be damaged during rehydration, the patient may make a complete recovery if proper supportive measures are instituted.
高渗性脱水在婴幼儿中是一种相当常见且可能非常危险的疾病。它发生在多种疾病的病程中。诱发因素包括中枢神经系统疾病、液体摄入量减少、因过度通气、出汗、腹泻和呕吐导致的液体丢失增加、醛固酮分泌增加(导致钠潴留)、婴儿较高的肾脏 obligatory 失水量以及用溶质含量相对较高的液体喂养婴儿的做法。如果主治医生了解诱发因素并做出早期诊断,然后使用含有一定盐分的溶液缓慢地对患者进行补液,那么结果很可能是良好的。即使在补液过程中大脑似乎受到了损伤,但如果采取适当的支持措施,患者仍可能完全康复。