原发性高血压患者对动态运动的心血管和交感神经反应。

Cardiovascular and sympathetic nervous response to dynamic exercise in patients with essential hypertension.

作者信息

Saitoh M, Miyakoda H, Kitamura H, Kinugawa T, Hisatome I, Kotake H, Mashiba H

机构信息

First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.

出版信息

Intern Med. 1992 May;31(5):606-10. doi: 10.2169/internalmedicine.31.606.

DOI:10.2169/internalmedicine.31.606

PMID:1387013

Abstract

To investigate the relationship among systolic blood pressure (SBP) during exercise (EX), left ventricular hypertrophy (LVH) and plasma norepinephrine concentration (NE) in patients with essential hypertension (HT), 20 patients with HT and 20 age- and sex-matched normal subjects were studied using treadmill testing. According to the change in SBP from rest to EX (delta SBP), patients with HT were classified into two groups (group I, n = 12, delta SBP less than 72 mmHg: group II, n = 8, delta SBP greater than or equal to 72 mmHg). There were no significant differences between the two groups with regard to SBP at rest, NE at rest and NE on EX. However, SBP at peak EX, delta SBP and the incidence of LVH were greater in group II than in group I. We conclude that exaggerated SBP response to EX in patients with HT is related to LVH.

摘要

为研究原发性高血压（HT）患者运动期间收缩压（SBP）、左心室肥厚（LVH）与血浆去甲肾上腺素浓度（NE）之间的关系，我们对20例HT患者及20例年龄和性别相匹配的正常受试者进行了跑步机测试。根据静息至运动时SBP的变化（ΔSBP），HT患者被分为两组（I组，n = 12，ΔSBP＜72 mmHg；II组，n = 8，ΔSBP≥72 mmHg）。两组在静息SBP、静息NE及运动时NE方面无显著差异。然而，II组运动高峰时的SBP、ΔSBP及LVH发生率均高于I组。我们得出结论，HT患者运动时SBP反应过度与LVH有关。