Wen Z H, Lai S L, Chen Y B
Training Center of Design, Measurement and Evaluation in Clinical Research, Guangzhou College of TCM.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Mar;12(3):157-9, 133.
20 patients with blood stasis syndrome (BSS), 20 patients with non-blood stasis syndrome (NBSS), and 17 normal subjects were measured by tests of RBC-C3b receptor rosette and RBC immune complex rosette. The rates of RBC-C3b receptor rosette formation (RBC-C3b RR, %) in BSS group, NBSS group and normal subjects were 20.90 +/- 4.02, 12.88 +/- 3.29 and 16.74 +/- 4.13 (P less than 0.01) respectively. The rates of RBC immune complex rosette formation (RBC-IC R, %) in the three groups were respectively 8.28 +/- 3.68, 7.73 +/- 2.48 and 7.41 +/- 2.43 (P less than 0.05). RBC-C3b RR was correlated to RBC-IC R in the normal subjects (r = 0.695, P less than 0.001). In patients with the same disease, RBC-C3b RR between the two syndromes (BSS and NBSS) was also very significantly different (P less than 0.01). This study suggested that there are variations on red cell immune function in BSS patients, and also provided an evidence that different syndromes of traditional Chinese medicine exist in diseases.
对20例血瘀证患者、20例非血瘀证患者及17例正常受试者进行红细胞 - C3b受体花环试验和红细胞免疫复合物花环试验检测。血瘀证组、非血瘀证组和正常受试者的红细胞 - C3b受体花环形成率(RBC - C3b RR,%)分别为20.90±4.02、12.88±3.29和16.74±4.13(P<0.01)。三组的红细胞免疫复合物花环形成率(RBC - IC R,%)分别为8.28±3.68、7.73±2.48和7.41±2.43(P<0.05)。正常受试者中,红细胞 - C3b RR与红细胞 - IC R相关(r = 0.695,P<0.001)。在患有相同疾病的患者中,两种证型(血瘀证和非血瘀证)之间的红细胞 - C3b RR也有非常显著差异(P<0.01)。本研究提示血瘀证患者红细胞免疫功能存在差异,也为疾病中存在中医不同证型提供了依据。