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一例腹壁皮下硬结移行八个月后出现胸腔积液的卫氏并殖吸虫病病例

[A case of Paragonimiasis westermani with pleural effusion eight months after migrating subcutaneous induration of the abdominal wall].

作者信息

Mizuki M, Mitoh K, Miyazaki E, Tsuda T

机构信息

Third Department of Medicine, Oita Medical University, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Jun;30(6):1125-30.

PMID:1387180
Abstract

Patients with Paragonimiasis westermani show a typical ring form or nodular shadow on chest X-ray, cough, sputum, and hemosputum. Recently, case reports of Paragonimiasis westermani, accompanied by pneumothorax and pleural effusion, as for Paragonimiasis miyazakii, have been increasing. Paragonimus westermani often causes an ectopic infection in various organs such as the peritoneal cavity, pleural cavity, pericardium, liver, adrenal gland and brain. Cutaneous paragonimiasis is considered one of the typical forms of ectopic infection in its earlier phase, but a few unexpected cases of cutaneous Paragonimiasis westermani have also been reported. A 68-year old man, who had never eaten fresh-water crab or raw sliced meat of wild boar, noticed subcutaneous induration of the abdominal wall. The induration had been gradually moving upwards and to the right from the infraumbilical region for over 20 days, and then disappeared at the right upper lateral abdominal wall. Eight months later, he developed severe pain in the right lower chest, and a chest X-ray showed right pleural effusion. Laboratory examinations revealed eosinophilia (WBC 3940/mm3, eosinophil 9%), elevated ESR, and an elevated serum total IgE level (5517 IU/ml). Ouchterlony's double diffusion test performed with the patient's serum in agarose showed strong bands toward Paragonimus westermani antigen, compared to Paragonimus miyazakii antigen. Immunoelectrophoresis with the patient's serum showed specific bands toward Paragonimus westermani antigen. This patient was finally diagnosed as having Paragonimiasis westermani infection, and he responded to praziquantel administration. The clinical course of this patient appears to be rare in cases of Paragonimiasis westermani infection. The clinical course of this case resembled some cases of Paragonimiasis miyazakii infection.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

卫氏并殖吸虫病患者胸部X线表现为典型的环形或结节状阴影,伴有咳嗽、咳痰和咯血。最近,与宫崎并殖吸虫病一样,伴有气胸和胸腔积液的卫氏并殖吸虫病病例报告不断增加。卫氏并殖吸虫常引起腹腔、胸腔、心包、肝脏、肾上腺和脑等各种器官的异位感染。皮肤并殖吸虫病在早期被认为是异位感染的典型形式之一,但也有一些意外的卫氏并殖吸虫皮肤感染病例报道。一名68岁男性,从未食用过淡水蟹或野猪生肉片,发现腹壁皮下硬结。硬结从脐下区域逐渐向上向右移动超过20天,然后在右上腹侧壁消失。八个月后,他右下胸部出现剧痛,胸部X线显示右侧胸腔积液。实验室检查显示嗜酸性粒细胞增多(白细胞3940/mm³,嗜酸性粒细胞9%)、血沉升高和血清总IgE水平升高(5517 IU/ml)。用患者血清在琼脂糖中进行的奥克特洛尼双扩散试验显示,与宫崎并殖吸虫抗原相比,对卫氏并殖吸虫抗原有强条带。患者血清免疫电泳显示对卫氏并殖吸虫抗原有特异性条带。该患者最终被诊断为卫氏并殖吸虫感染,对吡喹酮治疗有反应。该患者的临床病程在卫氏并殖吸虫感染病例中似乎很少见。该病例的临床病程与一些宫崎并殖吸虫感染病例相似。(摘要截短至250字)

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[A case of Paragonimiasis westermani with pleural effusion eight months after migrating subcutaneous induration of the abdominal wall].一例腹壁皮下硬结移行八个月后出现胸腔积液的卫氏并殖吸虫病病例
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Br J Radiol. 2012 Apr;85(1012):403-10. doi: 10.1259/bjr/30366021.
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Serial CT findings of Paragonimus infested dogs and the Micro-CT findings of the worm cysts.并殖吸虫感染犬的系列CT表现及虫囊肿的显微CT表现。
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