Simonetti G, Lupattelli L, Urigo F, Barzi F, Mosca S, Maspes F, Guazzaroni M
Istituto di Radiologia, II Università di Roma Tor Vergata.
Radiol Med. 1992 Jul-Aug;84(1-2):98-105.
Radiologic revascularization procedures--i.e., percutaneous transluminal angioplasty (PTA) and fibrinolysis--are a valuable alternative to surgery in the treatment of stenoses and occlusions of the visceral vessels, that is the celiac tripod and the superior and inferior mesenteric arteries. We treated 32 patients, 10 of them with acute mesenteric ischemia and 22 with chronic mesenteric ischemia and clinical signs of angina abdominis. Grüntzig or pre-shaped Cobra or Simmons balloons were employed (diameter: 5-7 mm, with variable length) when PTA was performed. Urokinase or rtPA was employed for fibrinolysis. In 3 cases acute mesenteric ischemia was not occlusive and could be successfully treated with papaverine infusion. In 7 cases, acute mesenteric ischemia was occlusive: in 5 of these patients it was successfully treated by PTA and/or fibrinolysis. Our results were positive in 80% of the cases, with remission of clinical signs in 4 of 5 patients treated for acute mesenteric ischemia. In 22 patients with chronic mesenteric ischemia, 26 stenotic occlusions were observed at angiography and 22 were treated with PTA, which was technically successful in 21 instances (early success rate: 85-95%). At 24 months, 10% of restenosis was observed. In our experience, PTA of the visceral district, possibly preceded by loco-regional infusion of fibrinolytic drugs, can be widely applied and yields excellent therapeutic results.
放射介入血管再通术,即经皮腔内血管成形术(PTA)和纤维蛋白溶解术,是治疗内脏血管狭窄和闭塞(即腹腔干和肠系膜上、下动脉)的一种有价值的手术替代方法。我们治疗了32例患者,其中10例为急性肠系膜缺血,22例为慢性肠系膜缺血并伴有腹部绞痛的临床症状。进行PTA时使用了Grüntzig球囊、预塑形Cobra球囊或Simmons球囊(直径:5 - 7mm,长度可变)。使用尿激酶或重组组织型纤溶酶原激活剂进行纤维蛋白溶解。3例急性肠系膜缺血并非闭塞性的,通过罂粟碱输注成功治疗。7例急性肠系膜缺血为闭塞性:其中5例患者通过PTA和/或纤维蛋白溶解术成功治疗。我们的结果在80%的病例中呈阳性,5例接受急性肠系膜缺血治疗的患者中有4例临床症状缓解。在22例慢性肠系膜缺血患者中,血管造影观察到26处狭窄闭塞,22处接受了PTA治疗,其中21例技术成功(早期成功率:85% - 95%)。在24个月时,观察到10%的再狭窄。根据我们的经验,内脏区域的PTA,可能先进行局部区域纤维蛋白溶解药物输注,可以广泛应用并产生优异的治疗效果。