去甲丙咪嗪（DMI）G 35020（丙咪嗪的一种代谢产物）的初步药理学和临床研究结果。 - Suppr

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超能文献

Preliminary pharmacological and clinical results with desmethylimipramine (DMI) G 35020, a metabolite of imipramine.

作者信息

BRODIE B, DICK P, KIELHOLZ P, POELDINGER W, THEOBALD W

出版信息

Psychopharmacologia. 1961 Dec 19;2:467-74. doi: 10.1007/BF00407446.

DOI:10.1007/BF00407446

PMID:13873299

Abstract

摘要

相似文献

Preliminary pharmacological and clinical results with desmethylimipramine (DMI) G 35020, a metabolite of imipramine.去甲丙咪嗪（DMI）G 35020（丙咪嗪的一种代谢产物）的初步药理学和临床研究结果。

Psychopharmacologia. 1961 Dec 19;2:467-74. doi: 10.1007/BF00407446.

Preliminary investigation of desmethylimipramine (G 35020).去甲丙咪嗪（G 35020）的初步研究。

Am J Psychiatry. 1962 Oct;119:370-1. doi: 10.1176/ajp.119.4.370.

[PRELIMINARY OBSERVATIONS ON THE CLINICAL USE OF A METABOLITE OF IMIPRAMINE: DESMETHYLIMIPRAMINE (G 35020)].

Riv Sper Freniatr Med Leg Alien Ment. 1963 Dec 31;87:1434-43.

Comparative clinical evaluation of lofepramine and imipramine. Pharmacological aspects.洛非帕明与丙咪嗪的临床比较评价。药理学方面。

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Kinetic effects of desmethylimipramine treatment on platelet serotonin uptake in depressed patients: a comparison with imipramine.

Psychiatry Res. 1991 Mar;36(3):299-305. doi: 10.1016/0165-1781(91)90028-n.

Plasma concentration monitoring of hydroxylated metabolites of imipramine and desipramine.

Drug Intell Clin Pharm. 1981 Apr;15(4):263-6. doi: 10.1177/106002808101500403.

Model for the kinetics of imipramine and its metabolites in adolescents.青少年体内丙咪嗪及其代谢物的动力学模型。

Ther Drug Monit. 1990 Sep;12(5):450-9. doi: 10.1097/00007691-199009000-00008.

Active metabolites of imipramine and desipramine in man.

Clin Pharmacol Ther. 1982 Mar;31(3):393-401. doi: 10.1038/clpt.1982.50.

Clinical trial with desmethylimipramine (G-35020), a new antidepressive compound.使用新型抗抑郁化合物去甲丙咪嗪（G - 35020）的临床试验。

Can Med Assoc J. 1962 Jun 2;86(22):1030-1.

SPECIES DIFFERENCES IN THE METABOLISM OF IMIPRAMINE AND DESMETHYLIMIPRAMINE (DMI).丙咪嗪和去甲丙咪嗪（DMI）代谢中的种属差异。

J Pharmacol Exp Ther. 1964 Jan;143:14-22.

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The Desmethyl Metabolite of Imipramine (G-35020) in the Treatment of Depression: Further Clinical Experience.丙咪嗪去甲基代谢物（G - 35020）治疗抑郁症：更多临床经验

Can Med Assoc J. 1963 Jun 1;88(22):1102-7.

A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.丙咪嗪、氯丙嗪及相关药物在涉及自主神经功能和利血平拮抗作用的各种试验中的比较。

Br J Pharmacol Chemother. 1964 Oct;23(2):330-50. doi: 10.1111/j.1476-5381.1964.tb01590.x.

IMIPRAMINE-DESMETHYLIMIPRAMINE. A PHARMACOLOGICAL STUDY ON HUMAN BEINGS.

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[DESIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS WITH A PSYCHODYNAMIC ANALYSIS OF ITS THERAPEUTIC EFFECTS].[地昔帕明（佩托弗兰）治疗抑郁症及其治疗效果的精神动力学分析]

Arch Psychiatr Nervenkr. 1964 Mar 16;205:192-203. doi: 10.1007/BF00352878.

PSYCHOPHARMACOLOGY OF IMIPRAMINE AND DESIPRAMINE: A COMPARATIVE STUDY OF THEIR EFFECTS IN NORMAL MALES.丙咪嗪和地昔帕明的精神药理学：对正常男性作用的比较研究

Psychopharmacologia. 1964 Apr 3;5:361-71. doi: 10.1007/BF00441447.

BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.丙咪嗪及其他药物与右旋苯丙胺、可卡因和丁苯那嗪相互作用的行为效应。

Psychopharmacologia. 1964 Feb 12;5:198-208. doi: 10.1007/BF00413242.

[ON THE METHODOLOGY OF RESEARCH ON ANTIDEPRESSIVE DRUGS WITH SPECIAL REFERENCE TO IMIPRAMINE (TOFRANIL) AND DESMETHYLIMIPRAMINE (PERTOFRAN)].[关于抗抑郁药物的研究方法，特别提及丙咪嗪（托弗尼尔）和去甲丙咪嗪（佩托弗兰）]

Arch Psychiatr Nervenkr. 1963 Sep 18;204:427-45.

COMPARISON BETWEEN IMIPRAMINE AND DESIPRAMINE IN NORMAL SUBJECTS AND THEIR ACTION IN DEPRESSIVE PATIENTS.

Psychopharmacologia. 1963 May 21;4:302-7. doi: 10.1007/BF00408186.

Clinical trial with desmethylimipramine (G-35020), a new antidepressive compound.使用新型抗抑郁化合物去甲丙咪嗪（G - 35020）的临床试验。

Can Med Assoc J. 1962 Jun 2;86(22):1030-1.

本文引用的文献

Pharmacological studies with tofranil.多虑平的药理学研究。

Can Psychiatr Assoc J. 1959;4(Suppl):75-85. doi: 10.1177/070674375900401s07.

[Metabolism of the psychopharmacological agent tofranil].[精神药理学药物丙咪嗪的代谢]

Arch Int Pharmacodyn Ther. 1960 Jul 1;126:454-69.

[Paper chromatographic determination of metabolic products of tofranil].[纸色谱法测定多虑平的代谢产物]

Med Esp. 1959;1:381-5.

On the mechanism of antidepressant action of imipraminelike drugs.关于丙咪嗪类药物抗抑郁作用的机制。

Ann N Y Acad Sci. 1962 Jan 13;96:279-88. doi: 10.1111/j.1749-6632.1962.tb50122.x.

Isolation from rat brain of a metabolic product, desmethylimipramine, that mediates the antidepressant activity of imipramine (Tofranil).从大鼠脑中分离出一种代谢产物去甲丙咪嗪，它介导丙咪嗪（托弗尼尔）的抗抑郁活性。

Experientia. 1961 Sep 15;17:417-8. doi: 10.1007/BF02157980.

Desmethylimipramine, a new type of antidepressant drug.

Med Exp Int J Exp Med. 1961;5:454-8. doi: 10.1159/000135120.

[On the pharmacology of tofranil (N-(3-dimethylaminopropyl)-iminodibenzyl hydrochloride].关于多虑平（N-（3-二甲氨基丙基）-亚氨基二苄基盐酸盐）的药理学

Arch Int Pharmacodyn Ther. 1959 Jul 1;120:450-89.

[The influence of Tofranil on the transmission of stimuli in the peripheral sympathetic nervous system].[多虑平对周围交感神经系统中刺激传递的影响]

Helv Physiol Pharmacol Acta. 1960;18:545-62.

[Treatment of depressive states with special consideration of tofranil, a new antidepressant].[以新型抗抑郁药多虑平为重点的抑郁状态治疗]

Schweiz Med Wochenschr. 1958 Aug 2;88(31):763-7.

[Treatment of depressive states with an iminodibenzyl derivative (G 22355)].用亚氨基二苄基衍生物（G 22355）治疗抑郁状态

Schweiz Med Wochenschr. 1957 Aug 31;87(35-36):1135-40.

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