Grosshans E, Tomb R
Faculté de Médecine, Universitaire de Strasbourg, France.
Allerg Immunol (Paris). 1992 Sep;24(7):256-61.
For etiologic checking of cutaneous vasculitis, skin testing may be of valuable help: epicutaneous patch-tests with delayed lecture (48 h.) performed with contact haptens (rubber allergens, azo dyes, resins ...) or drugs in pigmented progressive purpuric skin eruptions; prick-tests submitted to delayed (6-8 h.) clinic and histologic lecture, performed with miscellaneous drug or food-derived, microbial or environmental antigens in necrotizing vasculitis. In these conditions skin testing should be approached with great caution, because of the occurrence of non relevant positive reactions and the risk of precipitation of cutaneous or disseminated lesions of vasculitis.
对于皮肤血管炎的病因检查,皮肤试验可能会有很大帮助:对色素性进行性紫癜性皮疹进行接触性半抗原(橡胶过敏原、偶氮染料、树脂等)或药物的皮内斑贴试验(延迟48小时观察);对坏死性血管炎进行各种药物或食物来源、微生物或环境抗原的点刺试验,并延迟6 - 8小时进行临床和组织学观察。在这些情况下,进行皮肤试验时应格外谨慎,因为可能会出现无关的阳性反应,以及有诱发皮肤或播散性血管炎病变的风险。