沉默胆碱酯酶基因：一个小的高加索人群中的三个纯合子。
Silent cholinesterase gene: three homozygotes in a small Caucasian population.
作者信息
Santoro P, Lucci A, Tardi C
机构信息
Dipartimento di Pediatria, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.
出版信息
Boll Soc Ital Biol Sper. 1992 Mar;68(3):187-94.
PMID:1389075
Abstract
Three sera, showing only a 2-3% of the usual cholinesterase activity and belonging to two families of 800 Caucasian inhabitants of the same small town, were classified as type II silent cholinesterase genes by polyacrylamide slab gel electrophoresis, dibucaine and fluoride number and by their specific activity with acetyl- butyryl- or propionyl-thiocholine.
摘要
有三份血清，其胆碱酯酶活性仅为正常水平的2%-3%，这三份血清来自同一个小镇的800名白种居民中的两个家族，通过聚丙烯酰胺平板凝胶电泳、二丁卡因和氟化物值以及它们对乙酰硫代胆碱、丁酰硫代胆碱或丙酰硫代胆碱的比活性，被归类为II型沉默胆碱酯酶基因。
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