Nussbaum M, Treves T A, Korczyn A D
Department of Neurology, Sackler School of Medicine, Tel Aviv University, Israel.
Alzheimer Dis Assoc Disord. 1992 Summer;6(2):111-8. doi: 10.1097/00002093-199206020-00006.
Primary degenerative dementia (PDD) and multi-infarct dementia (MID) are the two most common categories of cognitive decline in old age. The definitions of these two clinical entities are currently based on clinical evaluation and on the exclusion of other underlying causes, and still lack a consensus. The DSM-III-R criteria are widely used for the diagnosis of dementia. However, their role in the differentiation between PDD and MID has not been thoroughly examined. A consecutive series of 98 demented patients who met the DSM-III-R criteria for dementia were admitted to a clinical study. Upon evaluating their type of dementia according to these criteria, 53 patients could not be diagnosed either as having PDD or MID. The DSM-III-R criteria for these two types of dementia are critically reviewed. Proposed modifications, aimed at refining their differential diagnostic role, are presented, enabling better allocation of demented patients into PDD, MID, or intermediate groups.
原发性退行性痴呆（PDD）和多发梗死性痴呆（MID）是老年认知功能衰退最常见的两类病症。这两种临床病症目前的定义基于临床评估以及对其他潜在病因的排除，且仍未达成共识。《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）标准被广泛用于痴呆症的诊断。然而，其在区分PDD和MID方面的作用尚未得到充分研究。连续98例符合DSM-III-R痴呆症标准的痴呆患者被纳入一项临床研究。根据这些标准评估他们的痴呆类型时，53例患者既不能被诊断为PDD也不能被诊断为MID。对这两种痴呆类型的DSM-III-R标准进行了批判性审查。提出了旨在完善其鉴别诊断作用的修改建议，以便能更好地将痴呆患者分为PDD、MID或中间组。
