Karimjee S, Brada M, Husband J, McCready V R
North Middlesex Hospital, London, U.K.
Eur J Cancer. 1992;28A(11):1856-7. doi: 10.1016/0959-8049(92)90021-s.
The role of gallium-67 single photon emission computed tomography (Ga-67 SPECT) in the assessment of mediastinal Hodgkin's disease was evaluated prospectively. Ga-67 SPECT and computed tomography (CT) were compared and correlated with clinical findings at initial presentation in 30 patients, 6 weeks after treatment, and 6 months later in 20 of the 30 patients. At initial presentation, active disease was detected on both imaging modalities on all occasions. 6 weeks after treatment CT showed residual mediastinal abnormality in 7 patients, whereas Ga-67 SPECT showed abnormal mediastinal tracer uptake in 3 patients. 6 months later CT showed residual mediastinal abnormality in 5 patients whereas all the Ga-67 SPECT studies were negative. Ga-67 SPECT imaging is a useful tool in assessing response to therapy in mediastinal Hodgkin's disease.
前瞻性评估了镓-67单光子发射计算机断层扫描（Ga-67 SPECT）在纵隔霍奇金病评估中的作用。对30例患者在初次就诊时、治疗6周后以及30例患者中的20例在6个月后的Ga-67 SPECT和计算机断层扫描（CT）进行了比较，并与临床表现进行了关联。初次就诊时，在所有情况下两种成像方式均检测到活动性疾病。治疗6周后，CT显示7例患者纵隔残留异常，而Ga-67 SPECT显示3例患者纵隔示踪剂摄取异常。6个月后，CT显示5例患者纵隔残留异常，而所有Ga-67 SPECT检查均为阴性。Ga-67 SPECT成像在评估纵隔霍奇金病的治疗反应中是一种有用的工具。
