Borghese M, Schiffino L, Vicario S, Galanti P, Giuliani A, Tocchi A, Caporale A, Terrinoni V
I Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi La Sapienza, Roma.
G Chir. 1992 Jun-Jul;13(6-7):371-5.
The authors report the diagnostic protocol used in the Breast Disease Unit of the 1st Surgical Department - University of Rome "La Sapienza" - (1987-1990) as well as the techniques for identifying and localizing nonpalpable lesions of the breast. Mammographic screening in women over 40 years, ultrasonography in women under 40 years, X-ray and ultrasound-guided fine needle aspiration and stereotactic guide wire placement with excisional biopsy, resulted to be diagnostic in 79 cases of carcinoma of the breast (2.0%) of which 13 (16.4%) were nonpalpable lesions. Moreover, the importance of nonpalpable lesions is discussed, pointing out how "very early" diagnosis of carcinoma of the breast plays a fundamental role with respect to both prognosis and treatment. The very early diagnosis of a "minimal" carcinoma ensures a significant increase in survival as well as more conservative surgical procedures that offer a better quality of life being less psychologically traumatic.
作者报告了罗马“La Sapienza”大学第一外科乳腺疾病科（1987 - 1990年）所采用的诊断方案，以及用于识别和定位乳腺不可触及病变的技术。40岁以上女性进行乳房X线筛查，40岁以下女性进行超声检查，X线和超声引导下细针穿刺以及立体定向导丝置入联合切除活检，对79例乳腺癌（占比2.0%）诊断成功，其中13例（占比16.4%）为不可触及病变。此外，文中讨论了不可触及病变的重要性，指出乳腺癌的“极早期”诊断在预后和治疗方面如何发挥着根本性作用。“微小”癌的极早期诊断可显著提高生存率，同时采用更保守的手术方式，因其心理创伤较小，能提供更好的生活质量。
