Bosman C, Bonucci E, Gugliantini P, Saguì L
Virchows Arch A Pathol Anat Histol. 1977 Feb 18;373(1):23-35. doi: 10.1007/BF00432466.
An ultrastructural study of chondrodystrophia calcificans congenita is reported. Foci of initial calcification of cartilage are characterized by coexistence of three different types of crystals, probably due to abnormal proteoglycan composition of cartilage matrix. The calcification process in chondrodystrophia calcificans congenita is apparently not related to 'matrix vesicles' as it is in normal cartilage.
本文报道了先天性钙化性软骨发育不良的超微结构研究。软骨初始钙化灶的特征是三种不同类型晶体共存，这可能是由于软骨基质蛋白聚糖组成异常所致。先天性钙化性软骨发育不良中的钙化过程显然与正常软骨中的“基质小泡”无关。
