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常规尸检中恶性肿瘤的发病率。

On the incidence of malignant tumors in routine autopsies.

作者信息

Niedobitk C, Niedobitek F, Pfitzinger H, Voss J D, Griesser G

出版信息

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Jan 21;88(2):157-84. doi: 10.1007/BF00284123.

Abstract

The present study taken over a 12-year time period analyzes malignant tumors in a large number of autopsies, with specific consideration of the frequency and location, age and sex group distribution, and histologic classification of the tumors. The tumors were first evaluated in terms of specific organs and organ systems and were then histologically classified. On a total of 23338 subjects who died between the years 1960 and 1971, 17052 autopsies were carried out (73.1%) and only 15384 (65.9%) of these were evaluated for out study. Altogether we located 4911 cases of MT, i.e., 31.9% of the evaluated autopsies. The number of MT in the males slightly exceeded that in the females (2508[51.1%] MT and 2403 [48.9%] MT, respectively.) We calculated over 60% of the MT to be in the 7th and 8th age groups. By comparing the two time periods (1960-1965) and 1966-1971) we calculated a significant increase in the MT rate by 1.7%. This increase was found mainly to effect the males (the female group showed only a slight increase). The greatest number of MT were located in the digestive system with an MT rate of 26.2%; next came the urogenital system (23.4%) and then the respiratory system (18.7%). The respiratory system took first position of importance in the males with an MT rate of 30.3% followed by the digestive system with 27.4%. The urogenital system dominated in the females with a rate of 29.0%. The rate of MT of the respiratory system was significantly higher in the males...

摘要

本研究在12年的时间里对大量尸检中的恶性肿瘤进行了分析,特别考虑了肿瘤的发生频率和部位、年龄和性别分布以及组织学分类。首先根据特定器官和器官系统对肿瘤进行评估,然后进行组织学分类。在1960年至1971年间死亡的23338名受试者中,共进行了17052例尸检(占73.1%),其中只有15384例(占65.9%)用于本研究评估。我们总共发现了4911例恶性肿瘤病例,即占评估尸检病例的31.9%。男性的恶性肿瘤病例数略多于女性(分别为2508例[占51.1%]和2403例[占48.9%])。我们计算得出超过60%的恶性肿瘤病例出现在第7和第8年龄组。通过比较两个时间段(1960 - 1965年)和(1966 - 1971年),我们计算出恶性肿瘤发病率显著上升了1.7%。这一上升主要影响男性(女性组仅略有上升)。恶性肿瘤病例数最多的是消化系统,发病率为26.2%;其次是泌尿生殖系统(23.4%),然后是呼吸系统(18.7%)。呼吸系统在男性中占首要地位,发病率为30.3%,其次是消化系统,为27.4%。泌尿生殖系统在女性中占主导地位,发病率为29.0%。男性呼吸系统的恶性肿瘤发病率显著更高……

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