Keitel W
Allerg Immunol (Leipz). 1976;22(3):303-5.
An analysis of the results of treatment-in five different hospitals and with such immunosuppressants as cyclophosphamide, azathioprine, and trenimone - of 550 patients with rheumatoid arthritis showed an overall rate of improvement of 36%. Cyclophosphamide, because of the relatively small number of side effects and the excellent therapeutical results obtained, proved to be much better than the other two immunosuppressive agents. Also, because the dosage required is comparatively low, patients over procreative age could be included in the program of treatment with immunosuppressants.
对五家不同医院使用环磷酰胺、硫唑嘌呤和曲尼莫德等免疫抑制剂治疗的550例类风湿关节炎患者的治疗结果进行分析，结果显示总体改善率为36%。由于副作用相对较少且治疗效果良好，环磷酰胺被证明比其他两种免疫抑制剂要好得多。此外，由于所需剂量相对较低，育龄以上患者也可纳入免疫抑制剂治疗方案。
