Gómez Camacho E, Cuello J A, Muñoz Lucena F, Pérez Pérez M, Causse M, Torres M, Kindelan J M
Servicio de Medicina Interna, Hospital General de Huelva.
Enferm Infecc Microbiol Clin. 1992 May;10(5):259-66.
To know the clinical features of tuberculosis in our environment, to evaluate its diagnostic techniques and therapeutic options as well as the evolution of patients.
Multicenter retrospective study of 1115 patients with tuberculosis, diagnosed between 1984 and 1988 in the population based areas of 7 Hospitals from Andalusia (Spain).
The mean age was less than 40 ages, the exponential growing of the number of cases a year in which the influence of drug addicts could be an important factor, an elevated proportion (45%) of extrapulmonary tuberculosis and disseminated forms, and a social environment of 20% of cases being alcoholics or drug addicts. A good use of diagnostic techniques is recorded, although the use of culture as diagnostic tools is lacking. The usual treatment was three drugs for nine months. The global evolution seems good. However a global mortality of 6.4% is recorded, mainly in disseminated forms and among patients with risk factors for developing tuberculosis.
We have seen an increment among tuberculosis cases, as well as a change in the clinical spectrum of the disease, linked to social illness and drug addiction. The diagnostic approach to tuberculosis seems to be appropriate. The follow up of patients is somewhat confusing.
为了解我们环境中结核病的临床特征，评估其诊断技术、治疗选择以及患者的病情演变。
对1984年至1988年间在西班牙安达卢西亚7家医院的社区人群中诊断出的1115例结核病患者进行多中心回顾性研究。
平均年龄小于40岁，每年病例数呈指数增长，其中吸毒者的影响可能是一个重要因素，肺外结核和播散型比例较高（45%），20%的病例有酗酒或吸毒的社会背景。记录显示诊断技术使用良好，但缺乏将培养作为诊断工具的应用。通常的治疗是使用三种药物治疗九个月。总体病情演变似乎良好。然而，记录的总体死亡率为6.4%，主要发生在播散型病例以及有结核病发病危险因素的患者中。
我们发现结核病病例有所增加，以及与社会疾病和药物成瘾相关的疾病临床谱发生了变化。结核病的诊断方法似乎是合适的。患者的随访情况有些混乱。
