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关于胃癌与胃溃疡关系的实验研究。

An experimental study of gastric cancer in relation to gastric ulcer.

作者信息

STEIN-WERBLOWSKY R

出版信息

Gut. 1962 Jun;3(2):129-34. doi: 10.1136/gut.3.2.129.

DOI:10.1136/gut.3.2.129
PMID:13916656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1413318/
Abstract

This experimental study shows that carcinogens are relatively harmless on intact gastric mucosa but can induce lesions when the mucosa has been damaged, particularly when the injury is deep as in gastrostomy. Human gastric carcinogenesis is discussed in the light of these findings.

摘要

这项实验研究表明，致癌物对完整的胃黏膜相对无害，但当黏膜受损时，尤其是像胃造口术那样损伤较深时，致癌物会诱发病变。根据这些发现对人类胃癌发生机制进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/568ea636cecc/gut00673-0051-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/27c3b742fc55/gut00673-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/d4ba6a4b5893/gut00673-0052-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/0bef2a778d46/gut00673-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/568ea636cecc/gut00673-0051-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/27c3b742fc55/gut00673-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/d4ba6a4b5893/gut00673-0052-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/0bef2a778d46/gut00673-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddcf/1413318/568ea636cecc/gut00673-0051-b.jpg

相似文献

1
An experimental study of gastric cancer in relation to gastric ulcer.关于胃癌与胃溃疡关系的实验研究。
Gut. 1962 Jun;3(2):129-34. doi: 10.1136/gut.3.2.129.
2
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ABO(H) blood group substances of the gastric juice in peptic ulcer, cancer of the stomach, and atrophic lesions of the gastric mucosa.消化性溃疡、胃癌及胃黏膜萎缩性病变患者胃液中的ABO（H）血型物质
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本文引用的文献

1
The relationship of gastric ulcer to gastric cancer; panel discussion.胃溃疡与胃癌的关系；小组讨论
Cancer. 1950 May;3(3):515-52. doi: 10.1002/1097-0142(1950)3:3<515::aid-cncr2820030313>3.0.co;2-z.
2
Precancerous and cancerous lesions of the fore-stomach and dermal-subcutaneous tumors in rats fed p-dimethylaminobenzene-1-azo-1-naphthalene.用对二甲氨基苯-1-偶氮-1-萘喂养的大鼠前胃的癌前和癌性病变以及皮肤-皮下肿瘤。
J Natl Cancer Inst. 1952 Aug;13(1):57-71.
3
Tumors of the glandular stomach induced in rats by intramural injection of 20-methylcholanthrene.
通过壁内注射20-甲基胆蒽在大鼠中诱发的腺胃肿瘤。
J Natl Cancer Inst. 1952 Apr;12(5):1019-55.
4
Variation in susceptibility of the fundic and pyloric portions of the glandular stomach of the rat to induction of neoplasia by 20-methylcholanthrene.大鼠腺胃胃底部和幽门部对20-甲基胆蒽诱导肿瘤形成的易感性差异。
Acta Unio Int Contra Cancrum. 1950 Jul;7(1):176-7.
5
Some observations on chemical carcinogenesis using new types of solvents for the carcinogenic hydrocarbons.关于使用新型溶剂溶解致癌碳氢化合物进行化学致癌作用的一些观察
Acta Unio Int Contra Cancrum. 1950 Jul;7(1):160-6.
6
Attempts to produce gastric carcinoma experimentally in a gastric ulcer.在胃溃疡中通过实验诱导胃癌的尝试。
Cancer Res. 1950 Nov;10(11):684-5.
7
[Long-term prognosis of colitis ulcerosa patients].[溃疡性结肠炎患者的长期预后]
Langenbecks Arch Klin Chir Ver Dtsch Z Chir. 1960;293:558-70.
8
[The pathogenesis of stomach cancer].[胃癌的发病机制]
Arch De Vecchi Anat Patol. 1960;31:149-62.
9
Experimental observations on the etiology of gastric carcinoma. II. The effect of heat, browned overheated fats, food dyes and carcinogenic hydrocarbons on the gastric mucosa.胃癌病因的实验观察。II. 热、过度褐变的过热脂肪、食用色素和致癌碳氢化合物对胃黏膜的影响。
Gastroenterology. 1955 Mar;28(3):345-59.
10
A study of the sensitivity of the mouse forestomach toward certain polycyclic hydrocarbons.小鼠前胃对某些多环烃敏感性的研究。
J Natl Cancer Inst. 1959 Oct;23:833-9.