尿抑胃素与促性腺激素之间的关系。
The relation between urogastrone and gonadotrophins.
作者信息
PERERA B A, ROSENOER V M
出版信息
Br J Pharmacol Chemother. 1963 Jun;20(3):534-9. doi: 10.1111/j.1476-5381.1963.tb01490.x.
Abstract
A commercial preparation of chorionic gonadotrophin inhibited gastric acid secretion induced by carbachol in rats. When the preparation was incubated for 10 min at 100 degrees C and pH 7, its gonadotrophic activity, as measured by a simple quantal assay based on the male toad spermiation response, was reduced by 92%. The inhibition of gastric acid secretion by the preparation was not significantly reduced by this treatment. It is concluded that the two activities are separable.
摘要
一种绒毛膜促性腺激素的商业制剂可抑制卡巴胆碱诱导的大鼠胃酸分泌。当该制剂在100℃和pH 7条件下孵育10分钟时，通过基于雄性蟾蜍排精反应的简单定量测定法测得，其促性腺活性降低了92%。但该处理并未显著降低该制剂对胃酸分泌的抑制作用。由此得出结论，这两种活性是可分离的。
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