Lin W J, Anderson J W
J Nutr. 1977 Apr;107(4):584-95. doi: 10.1093/jn/107.4.584.
Normal and streptozotocin-diabetic rats were fed a low carbohydrate diet or one of two high carbohydrate diets (sucrose or starch-bran). High carbohydrate diets were associated with slightly higher plasma glucose levels in both control and diabetic rats. However, glucose tolerance tests were not altered by the diets in either the control or diabetic rats. Plasma and liver triglyceride values for control and diabetic rats fed the high sucrose diet were similar to those of rats fed the low carbohydrate diet. The starch-bran diet was associated with lower plasma and liver triglyceride values in both control and diabetic rats. Plasma triglyceride values of diabetic rats fed the high sucrose diet or the low carbohydrate diet were significantly higher than values of control rats fed the same diets. On the other hand, plasma triglyceride values of diabetic rats fed the starch-bran diet were similar to values for control rats fed the same diet. These studies suggest that a high carbohydrate diet containing starch and wheat bran is associated with a reduction in plasma triglyceride values in both normal and diabetic rats. Liver glycolytic enzyme activities were significantly lower in diabetic rats than in control rats in all three dietary groups.
正常大鼠和链脲佐菌素诱导的糖尿病大鼠分别喂食低碳水化合物饮食或两种高碳水化合物饮食之一（蔗糖或淀粉麸）。在对照大鼠和糖尿病大鼠中，高碳水化合物饮食均与略高的血糖水平相关。然而，无论是对照大鼠还是糖尿病大鼠，饮食均未改变葡萄糖耐量试验结果。喂食高蔗糖饮食的对照大鼠和糖尿病大鼠的血浆和肝脏甘油三酯值与喂食低碳水化合物饮食的大鼠相似。在对照大鼠和糖尿病大鼠中，淀粉麸饮食均与较低的血浆和肝脏甘油三酯值相关。喂食高蔗糖饮食或低碳水化合物饮食的糖尿病大鼠的血浆甘油三酯值显著高于喂食相同饮食的对照大鼠。另一方面，喂食淀粉麸饮食的糖尿病大鼠的血浆甘油三酯值与喂食相同饮食的对照大鼠相似。这些研究表明，含有淀粉和麦麸的高碳水化合物饮食与正常大鼠和糖尿病大鼠血浆甘油三酯值的降低有关。在所有三个饮食组中，糖尿病大鼠的肝脏糖酵解酶活性均显著低于对照大鼠。
