Bachner E J, Konsens R M, Priem L, King T, Froimson A I
Department of Orthopaedic Surgery, Mt. Sinai Medical Center, Cleveland, Ohio.
Clin Orthop Relat Res. 1992 Oct(283):261-4.
A case of reversible vasospasm is reported in a 54-year-old man with a closed bimalleolar ankle fracture. On admission the patient had normal distal pulses and laboratory studies. He was a heavy smoker who continued to smoke in the hospital. Deep venous thrombosis (DVT) prophylaxis included dihydroergotamine and heparin (DHE-H). In the early postoperative period, marked spasm of all three arteries developed on the operative side. Smoking privileges and DHE-H were discontinued. The vasospasm resolved after intraarterial nitroglycerin. This case suggests an infrequent but potentially limb-threatening complication of DHE-H.
本文报道了一例54岁闭合性双踝骨折男性患者发生可逆性血管痉挛的病例。入院时患者远端脉搏及实验室检查均正常。他是一名重度吸烟者，住院期间仍继续吸烟。深部静脉血栓形成（DVT）预防措施包括双氢麦角胺和肝素（DHE-H）。术后早期，术侧所有三条动脉均出现明显痉挛。吸烟特权及DHE-H停用。动脉内注射硝酸甘油后血管痉挛缓解。该病例提示DHE-H存在一种罕见但可能危及肢体的并发症。
